Some difficulties, with this – any help appreciated – all covered below. (thanks Neildubya for explaining it)
Solving time (if I’m right about the doubtful one): 24 mins
* = anagram
ACROSS
1 S KATE BOARD “Second woman to join the bosses – that gives an opportunity for 10”
See notes on 10 across below
10 “Actor taking drug company apart” (Cocaine less co – thanks Neildubya)( This is my doubtful one C?I?E (All the crossing entries are covered in this blog). My guess is Michael CAINE, the film actor, but I confess that, if that is so, I cannot understand the wordplay at all. There are a few other words that fit. Will update when solution appears on Sunday (or beforehand if anyone can advise). What does it have to do with 1 across? Usually, when I think there may be a mistake in a crossword, I find it’s my own mistake, but I am tempted here to think 10 should be 12 (see 12 across below), but maybe another answer for 10 would explain it.
11 S EMBLANCE (been calm)*
12 W (HEEL I) E You could do this with a skateboard, so I wonder if that should be the link to 1 across.
13 A PO GEAN
14 AFTER S
21 STATION (ery)
21 C (ADD IS) H add = sum
25 IT (IN) ERATE
26 VIRUS (survi)* 5/7 is close to 70%
27 MA’S TERM IND
DOWN
2 (1st word crossing 10 across) KNEEL “Neil” or “Neal” No doubts about this.
3 TA’S SET
5 ALL COMERS Fave clue.
6 DANTE ALIGHIERI (right idea a line)* Very appropriate wording for anagram.
7 (2nd crossing 10 across) SCOW(l) Looks right, but with just one certain letter (W), maybe it’s something else…
8 (3rd crossing 10 across) LIBERTARIANISM (Librarians, time)* Another very good clue. No doubts about this.
9 LEAN E (D ON) Don = fellow
16 S AY
18 (c)LINK AGE
20 S CREAM
23 DE (V O) N
24 HO (u) SE U = Uranium (radioactive element).
10A – might this be (co)CAINE?
Apologies for this. I did pick this up in the checking and confirmed with Quixote that the reference in 1 Across should have been 12 rather than 10, but somehow seem to have failed to make the correction on the finished version. Mea culpa.
More humble pie for the 10/12 confusion – sorry!